Kodeīna un nomierinošu zāļu, piemēram, benzodiazepīnu vai tiem līdzīgu zāļu, vienlaicīga lietošana var izraisīt sedāciju, elpošanas nomākumu, komu un nāvi. Minētā riska dēļ šīs zāles vienlaicīgi varētu parakstīt pacientiem, kuriem nav iespējama alternatīva ārstēšana.Regulāra alkohola lietošana var samazināt parace
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